Ethanol → Methacrolein diethylacetal
반응식
O=[CH:2][C:3](=C)[CH3:4].C(O)C.C(O[CH:12]([O:16][CH2:17][CH3:18])[O:13][CH2:14][CH3:15])C>C1(C)C=CC(S(O)(=O)=O)=CC=1.C([O-])([O-])=O.[K+].[K+].C(Cl)Cl>[CH2:17]([O:16][CH:12]([O:13][CH2:14][CH3:15])[C:3](=[CH2:2])[CH3:4])[CH3:18]참가 물질
7
실험 절차
p-Toluenesulfonic acid (1.14 g, 0.006 mol) was added to a mixture of methacrolein (42.35 g, 0.06 mol), ethanol (141.9 mL), CH2Cl2 (120 mL) and triethylorthoformate (130.6 mL, 0.785 mol). The mixture was stirred at room temperature for 3 days and then K2CO3 (2 g) was added. The mixture was stirred for 10 minutes, filtered, and then the filtrate was concentrated in vacuo. The residue was purified by distillation through a Vigreaux column at 130° C. to afford 35 g of methacrolein diethylacetal.
후처리
- stirringThe mixture was stirred for 10 minutes
- filtrationfiltered
- concentrationthe filtrate was concentrated in vacuo
- distillationThe residue was purified by distillation through a Vigreaux column at 130° C.
출처 및 근거
- ORD 기록
- ord-c242999875e24297bc3dcc641e9fa88f
- 출처 데이터셋
- uspto-grants-1995_01
- 특허 번호
- US05380729
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