Ammonia → 2-Nitrophenyl phenyl ether

HRID 1769828

반응식

HRID 1769828 반응식
Cl[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N+:8]([O-:10])=[O:9].[C:11]1([O-:17])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.[Na+].N>>[CH:14]1[CH:15]=[CH:16][C:11]([O:17][C:2]2[C:3]([N+:8]([O-:10])=[O:9])=[CH:4][CH:5]=[CH:6][CH:7]=2)=[CH:12][CH:13]=1

참가 물질

4

반응물 3

HCID 222AmmoniaHCID 69451-Chloro-2-nitrobenzeneHCID 4445035Phenolate Sodium

생성물 1

HCID 166612-Nitrophenyl phenyl ether수율 93.9%

실험 절차

A steel autoclave was filled with 157.6 g of o-chloronitrobenzene and 116.1 g of sodium phenolate. At room temperature, 150 g of liquid ammonia were pumped into the vessel, the mixture was heated to 600 with stirring for 15 hours and subsequently cooled. Removal of the ammonia by distillation and workup of the distillation residue gave 202 g of 2-nitrodiphenyl ether (94% of the theoretical yield), 98.5% pure.

후처리

  1. customAt room temperature
  2. temperaturethe mixture was heated to 600
  3. temperaturesubsequently cooled
  4. customRemoval of the ammonia
  5. distillationby distillation and workup of the distillation residue

출처 및 근거

ORD 기록
ord-26fcceed456e444982cc43b30c71f271
출처 데이터셋
uspto-grants-1995_01
특허 번호
US05382686

연결된 노트

불러오는 중…