tert-butyl 4-(1H-pyrazol-1-yl)piperidine-1-carboxylate → 4-(1H-Pyrazol-1-yl)piperidine

HRID 1804593

반응식

HRID 1804593 반응식
[N:1]1([CH:6]2[CH2:11][CH2:10][N:9](C(OC(C)(C)C)=O)[CH2:8][CH2:7]2)[CH:5]=[CH:4][CH:3]=[N:2]1>Cl.O1CCOCC1>[N:1]1([CH:6]2[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]2)[CH:5]=[CH:4][CH:3]=[N:2]1

참가 물질

4

반응물 1

HCID 67971778tert-butyl 4-(1H-pyrazol-1-yl)piperidine-1-carboxylate

생성물 1

HCID 211930454-(1H-Pyrazol-1-yl)piperidine수율 96%

시약·촉매·용매 2

HCID 313Hydrochloric Acid용매HCID 312751,4-Dioxane용매

실험 절차

The title compound from Step B above (50 mg, 0.2 mmol) was dissolved in 4 M HCl in dioxane (2.0 mL) and stirred at RT for 1 h. The product was concentrated under reduced pressure and dried under high vacuum to give the title compound (i-17) (30 mg, 96%). ESI-MS calculated for C81H13N3: Exact Mass: 151.11. Found 152.10.

후처리

  1. concentrationThe product was concentrated under reduced pressure
  2. customdried under high vacuum

출처 및 근거

ORD 기록
ord-82c09d36b50e44e199295577f8c352ee
출처 데이터셋
uspto-grants-2013_01
특허 번호
US08354403B2

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