Dimethyl Sulfoxide → Cinnamoylbenzene

HRID 1831017노트

반응식

HRID 1831017 반응식
CO[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]=[CH:10][C:11]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[O:12].[C-]#N.[Na+].CS(C)=O.C(Cl)(Cl)Cl>O>[C:4]1([CH:9]=[CH:10][C:11]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[O:12])[CH:3]=[CH:8][CH:7]=[CH:6][CH:5]=1

참가 물질

6

반응물 4

HCID 679Dimethyl SulfoxideHCID 6212ChloroformHCID 8929Sodium CyanideHCID 2238302-Methoxychalcone

생성물 1

HCID 7189Cinnamoylbenzene

시약·촉매·용매 1

HCID 962Water용매

실험 절차

10 g of methoxy chalcone and 2.05 g of sodium cyanide are dissolved into 100 ml of dimethyl-sulfoxide, and then reacted for 24 hours. After the reaction, the reacted solution is mixed with chloroform and agitated together with distilled water so as to extract impurities. After removing the solution phase, the solution is decompressed at a room temperature in order to eliminate chloroform. After recrystallization of the remained solid phase in methanol, the solution is dried under vacuum, thus obtaining 4-hydroxychalcone for photoreaction.

후처리

  1. customreacted for 24 hours
  2. customAfter the reaction
  3. extractionto extract impurities
  4. customAfter removing the solution phase
  5. customis decompressed at a room temperature in order
  6. customAfter recrystallization of the remained solid phase in methanol
  7. dry with materialthe solution is dried under vacuum, thus obtaining 4-hydroxychalcone for photoreaction

출처 및 근거

ORD 기록
ord-f27c30dc0fc541219e008cf0617f4a65
출처 데이터셋
uspto-grants-2006_06
특허 번호
US07067566B2

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