Sodium Hydroxide → HCID 178526436, 화합물

HRID 1837506노트

반응식

HRID 1837506 반응식
[CH2:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH:2]1[C:10]1[N:11]=[CH:12][NH:13][CH:14]=1.[N+:15]([O-])([OH:17])=[O:16].NC(N)=O.[OH-].[Na+]>S(=O)(=O)(O)O>[N+:15]([C:6]1[CH:5]=[C:4]2[C:9](=[CH:8][CH:7]=1)[CH2:1][CH:2]([C:10]1[N:11]=[CH:12][NH:13][CH:14]=1)[CH2:3]2)([O-:17])=[O:16]

참가 물질

5

반응물 3

HCID 14798Sodium HydroxideHCID 31295Urea nitrateHCID 178419880HCID 178419880, 화합물

생성물 1

HCID 178526436HCID 178526436, 화합물

시약·촉매·용매 1

HCID 1118Sulfuric Acid용매

실험 절차

5 g of 4-indan-2-yl-1H-imidazole are dissolved at 0° C. in 140 ml of pure sulphuric acid, and then 1 equivalent of urea nitrate in powder form is added in small portions. The reaction mixture is poured onto ice, rendered alkaline using sodium hydroxide solution and extracted with ethyl acetate. The expected product is obtained after evaporation.

후처리

  1. additionThe reaction mixture is poured onto ice
  2. extractionextracted with ethyl acetate

출처 및 근거

ORD 기록
ord-699b92fbdbb54594a794bbccc449e70a
출처 데이터셋
uspto-grants-2004_08
특허 번호
US06784183B2

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