[CH3:1][O:2][C:3]1[CH:31]=[C:30]([O:32][CH3:33])[CH:29]=[CH:28][C:4]=1[CH2:5][N:6]1[C:15]2[C:10](=[CH:11][CH:12]=[C:13]([N:16]3[CH2:19][CH2:18][C@H:17]3[CH2:20][OH:21])[N:14]=2)[C:9](=[O:22])[C:8]([C:23]([O:25]CC)=[O:24])=[CH:7]1.[OH-].[Li+].Cl.O>C(O)C>[CH3:1][O:2][C:3]1[CH:31]=[C:30]([O:32][CH3:33])[CH:29]=[CH:28][C:4]=1[CH2:5][N:6]1[C:15]2[C:10](=[CH:11][CH:12]=[C:13]([N:16]3[CH2:19][CH2:18][C@H:17]3[CH2:20][OH:21])[N:14]=2)[C:9](=[O:22])[C:8]([C:23]([OH:25])=[O:24])=[CH:7]1A mixture of EXAMPLE 4A (1 g) and 0.1M lithium hydroxide (40 mL) in ethanol (50 mL) was stirred for 24 hours, adjusted to pH 4 with 1M hydrochloric acid, treated with water, and filtered.
불러오는 중…