Toluene → Limonene diepoxide

HRID 1881808

반응식

CC1CC[C@@H](C(C)=C)CC=1.C([O-])([O-])=[O:12].C([O-])([O-])=O.OO.OO.OO.[Na+].[Na+].[Na+].[Na+].[C:29]1(=O)[O:34][C:32](=O)[C:31]2=CC=CC=C12.[C:40]1([CH3:46])[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=1>>[CH3:46][C:40]12[O:12][CH:45]1[CH2:44][CH:43]([C:32]1([CH3:31])[O:34][CH2:29]1)[CH2:42][CH2:41]2

참가 물질

반응물 4

HCID 1140Toluene

HCID 6811Phthalic Anhydride

HCID 159762Sodium percarbonate

HCID 440917(+)-Limonene

생성물 1

HCID 232703Limonene diepoxide수율 99%

반응 조건

온도: 60 °C

실험 절차

Limonene (1.36 g, 10 mmol) was dissolved in toluene (25 ml), and a composition containing sodium percarbonate (10.5 g, 66.7 mmol) and phthalic anhydride (14.8 g, 100 mmol) was added thereto. The mixture was stirred at 60° C. After 12 hours, the reaction solution was washed with water to thereby completely remove phthalic acid, sodium phthalate, and disodium phthalate, which were generated as by-products, and the remaining H2O2. Toluene was distilled off from the organic phase by distillation, and as a result, 1.66 g (99% yields) of limonene diepoxide with a GC purity of 100% was obtained.

후처리

additionwas added
washthe reaction solution was washed with water to thereby completely remove phthalic acid, sodium phthalate, and disodium phthalate, which
distillationToluene was distilled off from the organic phase by distillation

출처 및 근거

ORD 기록: ord-8e5798d827c14d6aa5c2a1d2210861c0
출처 데이터셋: uspto-grants-2012_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08318958B2

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