5-(p-Methoxybenzylidene)-hydantoin → 5-(4-Methoxy-benzyl)-hydantoin

HRID 1905816

반응식

HRID 1905816 반응식
[CH3:1][O:2][C:3]1[CH:16]=[CH:15][C:6]([CH:7]=[C:8]2[NH:12][C:11](=[O:13])[NH:10][C:9]2=[O:14])=[CH:5][CH:4]=1>[OH-].[Na+].[Ni]>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:7][CH:8]2[NH:12][C:11](=[O:13])[NH:10][C:9]2=[O:14])=[CH:15][CH:16]=1

참가 물질

4

반응물 1

HCID 947495-(p-Methoxybenzylidene)-hydantoin

생성물 1

HCID 957275-(4-Methoxy-benzyl)-hydantoin수율 82%

시약·촉매·용매 2

HCID 935Nickel촉매HCID 14798Sodium Hydroxide용매

실험 절차

218.2 g (1 mole) of 5-(4-methoxy-benzylidene)-hydantoin are dissolved in 2 l of a N sodium hydroxide solution and 50 g of wet Raney-nickel are added. The reaction mixture is worked up according to Example 6. Thus 180.6 g of the desired compound are obtained, yield 82 %. Mp.: 174° C.

후처리

  1. additionare added

출처 및 근거

ORD 기록
ord-3bdb2291c15f4aa781b7fd3ae40a6099
출처 데이터셋
uspto-grants-1987_03
특허 번호
US04647694

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