2-Amino-4-methylpyridine → 5-Iodo-4-methylpyridin-2-amine

HRID 1916168노트

반응식

HRID 1916168 반응식
[CH3:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([NH2:8])[CH:3]=1.C1C(=O)N([I:16])C(=O)C1>>[I:16][C:7]1[C:2]([CH3:1])=[CH:3][C:4]([NH2:8])=[N:5][CH:6]=1

참가 물질

3

반응물 2

HCID 15332-Amino-4-methylpyridineHCID 120273N-Iodosuccinimide

생성물 1

HCID 177501955-Iodo-4-methylpyridin-2-amine

실험 절차

The title compound is synthesized according to general procedure GP1 starting from 2.0 g (18 mmol) 4-methyl-pyridin-2-ylamine and 4.2 g (18 mmol) NIS. Yield after precipitation from the reaction mixture: 3.6 g (83%).

후처리

  1. customYield
  2. customafter precipitation from the reaction mixture

출처 및 근거

ORD 기록
ord-507c54bb7e3a491fba40e58d24e7d618
출처 데이터셋
uspto-grants-2013_12
특허 번호
US08618111B2

반응 노트

불러오는 중…