Hydrochloric Acid → Iminodiacetic acid
반응식
C([O:8][C:9](=[O:30])[CH2:10][NH:11][CH:12](C(OC(C)(C)C)=O)[C:13]([O:15]CC1C=CC=CC=1)=[O:14])C1C=CC=CC=1.Cl.CCOCC>O1CCOCC1>[NH:11]([CH2:12][C:13]([OH:15])=[O:14])[CH2:10][C:9]([OH:30])=[O:8]참가 물질
5
실험 절차
Boc-Iminodiacetic acid dibenzyl ester (4.5 g, 10.88 mmol) was dissolved in dioxane (15 mL), then 4.6 M HCl in dioxane (20 mL) was added. The mixture was stirred for 90 min at room temperature and Et2O (200 mL) was added. The crystalline product was filtered off, washed twice with Et2O and dried in vacuo to afford the title compound (3.58 g, 94.2%).
후처리
- filtrationThe crystalline product was filtered off
- washwashed twice with Et2O
- customdried in vacuo
출처 및 근거
- ORD 기록
- ord-d6abcf194b374ed8a9eea0430cb9b194
- 출처 데이터셋
- uspto-grants-2000_09
- 특허 번호
- US06124298
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