Benzene → Phthalimide

HRID 1973123노트

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HRID 1973123 반응식
[C:1]1(=O)[O:6][C:4](=[O:5])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.C=C(CCCC#N)CCCC#[N:18].C1C=CC=CC=1>P(=O)(O)(O)O.O>[C:1]1(=[O:6])[NH:18][C:4](=[O:5])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12

참가 물질

6

반응물 3

HCID 241BenzeneHCID 6811Phthalic AnhydrideHCID 30165315-Methylenenonanedinitrile

생성물 1

HCID 6809Phthalimide수율 199.4%

시약·촉매·용매 2

HCID 1004Phosphoric Acid촉매HCID 962Water용매

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온도
240 °C

실험 절차

225 g (1.52 moles) of phthalic anhydride, 121.5 g (0.75 mole) of 5-methylene-1,9-nonanedinitrile, 300 cc of benzene, 40 g of water and 2 g of phosphoric acid were placed in a 1-liter autoclave. The autoclave was closed, then purged with dry nitrogen. Following purging, the reactor was heated to 240° C for a period of 4 hours. After cooling, the reaction mixture was filtered. The filter solid, after being washed in 300 cc of benzene, filtered and dried, yielded 220 g of phthalimide having a melting point of 234°-238° C. Yield 100 percent.

후처리

  1. customThe autoclave was closed
  2. custompurged with dry nitrogen
  3. customFollowing purging
  4. temperatureAfter cooling
  5. filtrationthe reaction mixture was filtered
  6. washThe filter solid, after being washed in 300 cc of benzene
  7. filtrationfiltered
  8. customdried

출처 및 근거

ORD 기록
ord-235c45dc691d4055bfddb37114316e02
출처 데이터셋
uspto-grants-1976_12
특허 번호
US03996239

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