Dimethyl Sulfate → 2-Methyl-2-thiopseudourea sulfate
반응식
[N:1]1C2C=CC=CC=2N[C:2]=1[NH:10]C(O)=O.N[C:15](N)=[S:16].[S:18]([O:23]C)([O:21]C)(=[O:20])=[O:19]>>[S:18]([OH:23])([OH:21])(=[O:20])=[O:19].[CH3:15][S:16][C:2](=[NH:1])[NH2:10]참가 물질
4
실험 절차
U.S. Pat. No. 3,010,968 describes a process for making the 2-benzimidazolecarbamic.acid esters of formula (I) by reacting thiourea with dimethyl sulfate to produce 2-methylthiopseudourea sulfate. This reaction product is then reacted with an alkyl chloroformate and a base to produce an acylated 2-methylthiopseudourea, which is then reacted further with an o-phenylenediamine in the presence of a protonic acid to produce the desired product.
출처 및 근거
- ORD 기록
- ord-79399c9652db476994ff5d162b1fe235
- 출처 데이터셋
- uspto-grants-1976_12
- 특허 번호
- US03997553
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