Chloroform → HCID 18766188, 화합물

HRID 19749

반응식

HRID 19749 반응식
[NH2:1][O:2][CH2:3][CH:4]([OH:12])[CH2:5][N:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1.C(Cl)(Cl)Cl.[CH2:17]([N:24]=[C:25]=[O:26])[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23]>>[OH:12][CH:4]([CH2:5][N:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)[CH2:3][O:2][NH:1][C:25]([NH:24][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])=[O:26]

참가 물질

4

반응물 3

HCID 6212ChloroformHCID 138341n-Heptyl isocyanateHCID 187662101-(Aminooxy)-3-(piperidin-1-yl)propan-2-ol

생성물 1

HCID 18766188HCID 18766188, 화합물

실험 절차

To the solution of 1.23 g (7.1 mmol) of l-aminooxy-2-hydroxy-3-(1-piperidinyl)-propane dissolved in 20 ml of chloroform 1.0 g (7.1 mmol) of heptyl isocyanate was added and the reaction mixture was stirred for 20 hours. Solvent was evaporated in vacuum and the residue was purified by chromatography to give pure colorless oil. White crystalline product was obtained by triturating with petroleum ether.

후처리

  1. additionwas added
  2. customSolvent was evaporated in vacuum
  3. customthe residue was purified by chromatography
  4. customto give pure colorless oil
  5. customWhite crystalline product was obtained
  6. customby triturating with petroleum ether

출처 및 근거

ORD 기록
ord-5d41a87368eb46de9294345e9b841d10
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07745465B2

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