Azobisisobutyronitrile → (1-Bromo-2-oxopropyl) oxybenzene

HRID 1982548

반응식

HRID 1982548 반응식
[O:1]([CH2:8][C:9](=[O:11])[CH3:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Br:12]N1C(=O)CCC1=O.N(C(C)(C)C#N)=NC(C)(C)C#N>ClC(Cl)(Cl)Cl>[Br:12][CH:8]([O:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[C:9](=[O:11])[CH3:10]

참가 물질

5

반응물 3

HCID 6547AzobisisobutyronitrileHCID 67184N-bromobutanimideHCID 693131-Phenoxy-2-propanone

생성물 1

HCID 20161336(1-Bromo-2-oxopropyl) oxybenzene

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매

실험 절차

Phenoxy-2-propanone (0.10 mol), N-bromosuccinimide (0.10 mol) and a catalytic amount of 2,2'-azobis(2-methylpropionitrile) were stirred together in tetrachloromethane (100 ml) at 80° C. for 61/2 hours. The solvent was distilled off and the residue distilled under vacuum to give (1-bromo-2-oxopropyl) oxybenzene. Yield: 10.4 g (45%), b.p. 66°-68° C./0.01 mm Hg. 1H NMR (CDCl3, δ): 2.50 (s, CH3) 6.40 (s, --CHBr--), 6.9-7.5 (5H, Ph).

후처리

  1. distillationThe solvent was distilled off
  2. distillationthe residue distilled under vacuum

출처 및 근거

ORD 기록
ord-14f1c6fd78234849a932491a3d8d0b3e
출처 데이터셋
uspto-grants-1986_06
특허 번호
US04596870

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