Hydrochloric Acid → 2-[(2,6-Dichloropyridin-3-yl)oxy]propanoic acid
반응식
C([O:3][C:4](=[O:16])[CH:5]([O:7][C:8]1[C:9]([Cl:15])=[N:10][C:11]([Cl:14])=[CH:12][CH:13]=1)[CH3:6])C.Cl>[OH-].[Na+]>[Cl:15][C:9]1[C:8]([O:7][CH:5]([CH3:6])[C:4]([OH:16])=[O:3])=[CH:13][CH:12]=[C:11]([Cl:14])[N:10]=1참가 물질
4
실험 절차
105 g of 2-[(2,6-dichloro-3-pyridyl)oxy]propionic acid ethyl ester was refluxed with 550 ml of 1 N sodium hydroxide solution for 1 hour. The pH value of the solution was brought to 1.5 with concentrated hydrochloric acid and then filtered. Recrystallisation from ethanol/water yielded 58 g of the above acid, m.p. 128°-131°.
후처리
- filtrationfiltered
- customRecrystallisation from ethanol/water
출처 및 근거
- ORD 기록
- ord-70819602756749d0810aa2abea49662a
- 출처 데이터셋
- uspto-grants-1983_09
- 특허 번호
- US04404020
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