반응식
[CH3:1][C:2]([O:5][C:6]([N:8]1[CH2:25][c:24]([c:11]2[CH2:10][CH2:9]1)[c:15]([O:16][CH2:17][c:18]3[cH:23][cH:22][cH:21][cH:20][cH:19]3)[cH:14][c:13](Br)[cH:12]2)=[O:7])([CH3:4])[CH3:3].C[Si](c1ccccc1)(c2ccccc2)[C:26](O)=[O:27].CC[SiH](CC)CC>>[CH3:1][C:2]([O:5][C:6]([N:8]1[CH2:25][c:24]([c:11]2[CH2:10][CH2:9]1)[c:15]([O:16][CH2:17][c:18]3[cH:23][cH:22][cH:21][cH:20][cH:19]3)[cH:14][c:13]([CH:26]=[O:27])[cH:12]2)=[O:7])([CH3:4])[CH3:3]참가 물질
10
반응물 3
생성물 1
시약·촉매·용매 6
HCID 81531Diisopropylethylamine시약
HCID 448383(3R,4R,5R,6R)-5-acetamido-2-[[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-3-fluoro-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid시약
HCID 167845palladium(II) acetate촉매
HCID 178420544HCID 178420544, 화합물촉매
HCID 6228Dimethylformamide용매
HCID 117669-Phenylanthracene내부 표준반응 조건
- 온도
- 90 °C
출처 및 근거
- ORD 기록
- ord-bb981b38366741f496e5970875451bc0
- 출처 데이터셋
- 39k HTE dataset from Pfizer
- 원본 링크
- 출처 보기
연결된 노트
불러오는 중…