Triethyl phosphite → 5-(Diethylphosphono)pentyl acetate

반응식

[C:1]([O:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9]Br)(=[O:3])[CH3:2].[P:11]([O:18]CC)([O:15][CH2:16][CH3:17])[O:12][CH2:13][CH3:14]>>[C:1]([O:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][P:11]([O:15][CH2:16][CH3:17])([O:12][CH2:13][CH3:14])=[O:18])(=[O:3])[CH3:2]

참가 물질

반응물 2

HCID 31215Triethyl phosphite

HCID 851405-Bromopentyl acetate

생성물 1

HCID 196892225-(Diethylphosphono)pentyl acetate

실험 절차

100.34 g (0.48 mol) of 5-bromopentyl acetate were heated at 150° C. for 8 hours with 79.8 g (0.048 mol) of triethyl phosphite while stirring and passing in nitrogen. The mixture was then fractionally distilled under reduced pressure.

후처리

distillationThe mixture was then fractionally distilled under reduced pressure

출처 및 근거

ORD 기록: ord-37e8c73db5a4451484b91a4dd3cc9bb3
출처 데이터셋: uspto-grants-1998_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05728686

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