Diboron tetrahydroxide → 1-Methyl-1H-benzoimidazole-6-boronic acid

HRID 2018241

반응식

HRID 2018241 반응식
[OH:1][B:2](B(O)O)[OH:3].[CH3:4][n:5]1[c:13]([c:8]2[n:7][cH:6]1)[cH:12][c:11](Br)[cH:10][cH:9]2>>[CH3:4][n:5]1[c:13]([c:8]2[n:7][cH:6]1)[cH:12][c:11]([B:2]([OH:3])[OH:1])[cH:10][cH:9]2

참가 물질

8

반응물 2

HCID 10986154Diboron tetrahydroxideHCID 235376446-Bromo-1-methyl-1H-benzimidazole

생성물 1

HCID 467386791-Methyl-1H-benzoimidazole-6-boronic acid

시약·촉매·용매 5

HCID 516892Sodium Bicarbonate시약HCID 167845palladium(II) acetate촉매HCID 73357432DBtPF촉매HCID 64052-Methyl-2-butanol용매HCID 117669-Phenylanthracene내부 표준

반응 조건

온도
110 °C

출처 및 근거

ORD 기록
ord-cdd5ee000a314b2b88295e912fb7a68f
출처 데이터셋
39k HTE dataset from Pfizer
원본 링크
출처 보기

연결된 노트

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