Phosphorus trichloride → Diisopropylphosphoramidous dichloride

HRID 20197

반응식

HRID 20197 반응식
C(N([P:8]([N:10]([CH:14]([CH3:16])[CH3:15])[CH:11]([CH3:13])[CH3:12])[Cl:9])C(C)C)(C)C.P(Cl)(Cl)[Cl:18]>C(#N)C>[CH:11]([N:10]([P:8]([Cl:18])[Cl:9])[CH:14]([CH3:16])[CH3:15])([CH3:13])[CH3:12]

참가 물질

4

반응물 2

HCID 24387Phosphorus trichlorideHCID 2733425Bis(diisopropylamino)chlorophosphine

생성물 1

HCID 5139911Diisopropylphosphoramidous dichloride수율 81%

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

Bis-(N,N-Diisopropylamino) chlorophosphine, 10 grams (37 mmols), was dissolved in 500 ml of anhydrous acetonitrile. Phosphorus trichloride, 5.16 grams (37 mmols), was added to the solution and the reaction was allowed to stir over-night at room temperature. The reaction was assayed for completion by 31P NMR of an aliquot of the reaction using an external lock. Complete conversion of the starting material at δ 134 ppm to the product at δ 165 ppm was observed. The solvent was evaporated from the reaction mixture on a rotary evaporator and the resulting oil distilled under vacuum yielding 5.7 grams of product (81% yield).

후처리

  1. customThe solvent was evaporated from the reaction mixture on a rotary evaporator
  2. distillationthe resulting oil distilled under vacuum

출처 및 근거

ORD 기록
ord-0360ccbca2fd4ed99002b89ee7ec54f8
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07745591B2

연결된 노트

불러오는 중…