2,3-Dichloro-4-fluorobenzonitrile → HCID 59370509, 화합물
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[Cl:1][C:2]1[C:9]([Cl:10])=[C:8](F)[CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[CH3:12][C@H:13]1[C@@H:17]([OH:18])[CH2:16][CH2:15][NH:14]1>CS(C)=O.C(=O)([O-])[O-].[Li+].[Li+]>[Cl:1][C:2]1[C:9]([Cl:10])=[C:8]([N:14]2[CH2:15][CH2:16][C@H:17]([OH:18])[C@@H:13]2[CH3:12])[CH:7]=[CH:6][C:3]=1[C:4]#[N:5]참가 물질
5
실험 절차
Using 2,3-dichloro-4-fluorobenzonitrile (400.5 mg), 0.9 mol/L solution (2.35 mL) of (2S,3S)-2-methylpyrrolidin-3-ol in dimethyl sulfoxide and lithium carbonate (78 mg), the title compound was obtained as yellow crystals (yield: 417 mg) by an operation similar to that in Example 3.
출처 및 근거
- ORD 기록
- ord-af9ead7cdefb45b7b584e91bac71c226
- 출처 데이터셋
- uspto-grants-2013_11
- 특허 번호
- US08592452B2
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