2-Chloroethyl vinyl ether → 1-Cyclohexyl-4-[2-(ethenyloxy)ethoxy]benzene

HRID 2085005

반응식

HRID 2085005 반응식
[CH:1]1([C:7]2[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH:14]([O:16][CH2:17][CH2:18]Cl)=[CH2:15].[OH-].[Na+].C(N(CC)CC)C>C1(C)C=CC=CC=1.[Br-].C([N+](CCCC)(CCCC)CCCC)CCC>[CH:14]([O:16][CH2:17][CH2:18][O:13][C:10]1[CH:9]=[CH:8][C:7]([CH:1]2[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]2)=[CH:12][CH:11]=1)=[CH2:15]

참가 물질

7

반응물 4

HCID 80742-Chloroethyl vinyl etherHCID 8471TriethylamineHCID 143274-CyclohexylphenolHCID 14798Sodium Hydroxide

생성물 1

HCID 220116871-Cyclohexyl-4-[2-(ethenyloxy)ethoxy]benzene

시약·촉매·용매 2

HCID 74236Tetrabutylammonium Bromide촉매HCID 1140Toluene용매

실험 절차

p-Cyclohexylphenol (83.1 g) (0.5 mol) was dissolved in 300 ml of toluene. Subsequently, 150 g of 2-chloroethyl vinyl ether, 25 g of sodium hydroxide, 5 g of tetrabutylammonium bromide, and 60 g of triethylamine were added to the above solution and the solution was allowed to react at 120° C. for 5 hours. The reaction solution was washed with water and the excess amounts of chloroethyl vinyl ether and toluene were distilled off. The obtained oil was purified by distillation under reduced pressure, thereby 4-cyclohexylphenoxyethyl vinyl ether was obtained.

후처리

  1. customto react at 120° C. for 5 hours
  2. washThe reaction solution was washed with water
  3. distillationthe excess amounts of chloroethyl vinyl ether and toluene were distilled off
  4. distillationThe obtained oil was purified by distillation under reduced pressure

출처 및 근거

ORD 기록
ord-4589896e68224473bd3efea8e18ad43f
출처 데이터셋
uspto-grants-2004_04
특허 번호
US06720128B2

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