Dimethyl Sulfoxide → 4-Chloro-3-{5-[(2-cyclohexylethylamino)methyl]pyridin-2-yl}benzamide

HRID 209866노트

반응식

[CH3:35][S:36]([CH3:37])=[O:38].[Cl:1][c:2]1[c:3](-[c:10]2[n:11][cH:12][c:13]([CH2:16][NH:17][CH2:18][CH2:19][CH:20]3[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]3)[cH:14][cH:15]2)[cH:4][c:5]([C:6]#[N:7])[cH:8][cH:9]1.[K+:26].[K+:27].[O-:28][C:29]([O-:30])=[O:31].[OH2:34].[OH:32][OH:33]>>[Cl:1][c:2]1[c:3](-[c:10]2[n:11][cH:12][c:13]([CH2:16][NH:17][CH2:18][CH2:19][CH:20]3[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]3)[cH:14][cH:15]2)[cH:4][c:5]([C:6]([NH2:7])=[O:28])[cH:8][cH:9]1