Hydrochloric Acid → HCID 178524563, 화합물
반응식
[Cl:1][C:2]1[CH:19]=[CH:18][CH:17]=[CH:16][C:3]=1[C:4]([NH:6][C:7]1[NH:11][N:10]=[C:9]([C:12]([O:14]C)=[O:13])[CH:8]=1)=[O:5].O[Li].O.O.Cl>C1COCC1.CO>[Cl:1][C:2]1[CH:19]=[CH:18][CH:17]=[CH:16][C:3]=1[C:4]([NH:6][C:7]1[NH:11][N:10]=[C:9]([C:12]([OH:14])=[O:13])[CH:8]=1)=[O:5]참가 물질
7
실험 절차
A solution of 1.0 eq. of 22 and 5.0 eq. of LiOH.H2O in THF, MeOH, and H2O (2:1:1) was stirred at rt. After a time sufficient for reaction completion, the reaction mixture was rotary evaporated. The mixture was acidified with concentrated HCl. As the pH of the solution reached about 2, a precipitate formed. The solid was collected by filtration and after drying under vacuum, product 23 was obtained.
후처리
- customAfter a time sufficient for reaction completion
- customa precipitate formed
- filtrationThe solid was collected by filtration
- customafter drying under vacuum
출처 및 근거
- ORD 기록
- ord-15de893e919d4be48b68e6fdab966bcf
- 출처 데이터셋
- uspto-grants-2008_10
- 특허 번호
- US07432379B2
반응 노트
불러오는 중…