Sodium Hydroxide → N'-t-butyl-N-(3-toluoyl)-N'-benzoylhydrazine

HRID 21623

반응식

HRID 21623 반응식
[C:1]([N:5]([C:7](=[O:14])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[NH2:6])([CH3:4])([CH3:3])[CH3:2].[OH-].[Na+].[C:17]1([CH3:26])[CH:22]=[CH:21][CH:20]=[C:19]([C:23](Cl)=[O:24])[CH:18]=1>C1(C)C=CC=CC=1>[C:1]([N:5]([C:7](=[O:14])[C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1)[NH:6][C:23]([C:19]1[CH:18]=[C:17]([CH3:26])[CH:22]=[CH:21][CH:20]=1)=[O:24])([CH3:4])([CH3:2])[CH3:3]

참가 물질

5

반응물 3

HCID 14798Sodium HydroxideHCID 743753-Methylbenzoyl chlorideHCID 1275961N-(tert-butyl)benzohydrazide

생성물 1

HCID 15294604N'-t-butyl-N-(3-toluoyl)-N'-benzoylhydrazine

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

To a stirred mixture of N'-t-butyl-N'-benzoylhydrazine (1.0 g) in 15 ml toluene and aqueous sodium hydroxide (0.5 g of 50% NaOH) was added 3-toluoyl-chloride (0.9 g). After stirring for 2 hours, the product was isolated by filtration to give N'-t-butyl-N-(3-toluoyl)-N'-benzoylhydrazine in good yield: m.p. 111°-114° C.

후처리

  1. customthe product was isolated by filtration

출처 및 근거

ORD 기록
ord-32bba065ba434b10a71460d0eeef938b
출처 데이터셋
uspto-grants-1995_06
특허 번호
US05424333

연결된 노트

불러오는 중…