N'-t-butyl-N'-(3-methylbenzoyl)hydrazine → N'-t-butyl-N-(2-phenyl-3-methylpentanoyl)-N'-(3-toluoyl)hydrazine

HRID 21672

반응식

HRID 21672 반응식
[C:1]([N:5]([C:7]([C:9]1[CH:10]=[C:11]([CH3:15])[CH:12]=[CH:13][CH:14]=1)=[O:8])[NH2:6])([CH3:4])([CH3:3])[CH3:2].[C:16]1([CH:22]([CH:26]([CH3:29])[CH2:27][CH3:28])[C:23](Cl)=[O:24])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>C1(C)C=CC=CC=1.[OH-].[Na+]>[C:1]([N:5]([C:7]([C:9]1[CH:10]=[C:11]([CH3:15])[CH:12]=[CH:13][CH:14]=1)=[O:8])[NH:6][C:23](=[O:24])[CH:22]([C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1)[CH:26]([CH3:29])[CH2:27][CH3:28])([CH3:4])([CH3:3])[CH3:2]

참가 물질

5

반응물 2

HCID 15452040N'-t-butyl-N'-(3-methylbenzoyl)hydrazineHCID 218860263-Methyl-2-phenylvaleryl chloride

생성물 1

HCID 15452019N'-t-butyl-N-(2-phenyl-3-methylpentanoyl)-N'-(3-toluoyl)hydrazine

시약·촉매·용매 2

HCID 14798Sodium Hydroxide촉매HCID 1140Toluene용매

실험 절차

To a stirred suspension of N'-t-butyl-N'-(3-toluoyl)hydrazine (0.7 g) in toluene (10 ml) and aqueous sodium hydroxide (12 drops of 50% aqueous sodium hydroxide) was added dropwise 2-phenyl-3-methyl-pentanoyl chloride (1.0 g). The reaction mixture was stirred overnight, diluted with hexanes and the solids filtered. The solids were washed with hexane and air dried.

후처리

  1. filtrationthe solids filtered
  2. washThe solids were washed with hexane and air
  3. customdried

출처 및 근거

ORD 기록
ord-40b8df1381f7498e92be0080b88467a1
출처 데이터셋
uspto-grants-1995_06
특허 번호
US05424333

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