Triphenylphosphine → HCID 71075488, 화합물
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[CH2:1]([C:3]1[CH:4]=[C:5]([OH:9])[CH:6]=[CH:7][CH:8]=1)[CH3:2].C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.O[C@H:30]([CH3:35])[C:31]([O:33][CH3:34])=[O:32].CC(OC(/N=N/C(OC(C)C)=O)=O)C>C1COCC1>[CH2:1]([C:3]1[CH:4]=[C:5]([CH:6]=[CH:7][CH:8]=1)[O:9][C@@H:30]([CH3:35])[C:31]([O:33][CH3:34])=[O:32])[CH3:2]참가 물질
6
실험 절차
To 3-ethylphenol (3.42 g, 28 mmol) in THF (20 mL) at ice bath was added triphenylphosphine (9.5 g, 36.4 mmol) and then (R)-methyl 2-hydroxypropanoate (2.94 mL, 31 mmol). And then DIAD (8.2 mL, 42 mmol) was added dropwise to the above cole solution. The mixture was stirred at room temperature for 16 hr. The solvent was removed and the residue was purified by silica gel to obtain the title compound.
후처리
- customThe solvent was removed
- customthe residue was purified by silica gel
출처 및 근거
- ORD 기록
- ord-be5a6e8a8c8649f1aab0ba6376feb4e0
- 출처 데이터셋
- uspto-grants-2015_06
- 특허 번호
- US09051265B2
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