Ammonium Acetate → HCID 22482279, 화합물

HRID 2181915

반응식

HRID 2181915 반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5]([F:8])=[CH:4][C:3]=1[C:9]1[CH:14]=[C:13]([F:15])[CH:12]=[CH:11][C:10]=1[C:16](=O)[CH3:17].C([O-])(=O)C.[NH4+].C([BH3-])#[N:25].[Na+]>CO>[F:1][C:2]1[CH:7]=[CH:6][C:5]([F:8])=[CH:4][C:3]=1[C:9]1[CH:14]=[C:13]([F:15])[CH:12]=[CH:11][C:10]=1[CH:16]([NH2:25])[CH3:17]

참가 물질

5

반응물 3

HCID 517165Ammonium AcetateHCID 5003444Sodium cyanoborohydrideHCID 224822741-(2',5',5-Trifluoro-1,1'-biphenyl-2-yl)ethanone

생성물 1

HCID 22482279HCID 22482279, 화합물

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

The title compound was prepared from 1-(2′,5′,5-trifluoro-1,1′-biphenyl-2-yl)ethanone (650 mg, 2.6 mmol), anhydrous methanol (10 mL), ammonium acetate (4.0 g, 52 mmol), and sodium cyanoborohydride (326 g, 5.2 mmol) according to the procedure and in the same manner as described in Example 105, step b. The crude amine was immediately used without further purification in Example 116, step c;

후처리

  1. customThe crude amine was immediately used without further purification in Example 116, step c

출처 및 근거

ORD 기록
ord-85d4257011ad4af6afb5dfc5e879095a
출처 데이터셋
uspto-grants-2005_05
특허 번호
US06894061B2

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