Potassium Carbonate → Pteridine

HRID 2200210노트

반응식

HRID 2200210 반응식
Cl[C:2]1[N:11]=[CH:10][C:9]2[C:4](=[N:5][CH:6]=[CH:7][N:8]=2)[N:3]=1.[H-].[Na+].C(=O)([O-])[O-].[K+].[K+].C(N(C(C)C)CC)(C)C>C(N(CC)CC)C>[N:3]1[C:4]2[C:9](=[N:8][CH:7]=[CH:6][N:5]=2)[CH:10]=[N:11][CH:2]=1

참가 물질

6

반응물 4

HCID 11430Potassium CarbonateHCID 24758Sodium hydrideHCID 81531DiisopropylethylamineHCID 6405372-Chloropteridine

생성물 1

HCID 1043Pteridine

시약·촉매·용매 1

HCID 8471Triethylamine용매

실험 절차

Treatment of chloro-pteridine V′ with nuclephile R7LY, in the presence of a base, such as sodium hydride, potassium carbonate, triethylamine, and diisopropylethylamine, and optionally using a catalyst such as Pd(0), affords Pteridine compound VI′. Suitable solvent for this reaction includes chloroform, methylene chloride, toluene, and tetrahydrofuran.

출처 및 근거

ORD 기록
ord-d9c56d6283074992ae1b8b6cf1b5d281
출처 데이터셋
uspto-grants-2016_06
특허 번호
US09359361B2

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