Benzylamine → 4-(Benzylamino)but-3-en-2-one

HRID 2207145노트

반응식

HRID 2207145 반응식
[CH2:1]([NH2:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.CO[CH:11]=[CH:12][C:13](=[O:15])[CH3:14]>C(Cl)(Cl)Cl>[CH2:1]([NH:8][CH:11]=[CH:12][C:13](=[O:15])[CH3:14])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 7504BenzylamineHCID 942973-Buten-2-one, 4-methoxy-

생성물 1

HCID 5214434-(Benzylamino)but-3-en-2-one수율 70%

시약·촉매·용매 1

HCID 6212Chloroform용매

실험 절차

A mixture of benzylamine (1.1 mL, 10 mmol) and 4-methoxybut-3-en-2-one (1 mL, 10 mmol) in chloroform (100 mL) was stirred at room temperature until complete conversion. Then, the solvent was evaporated to afford the desired product 30 in 70% yield which was used without additional purification.

후처리

  1. customThen, the solvent was evaporated

출처 및 근거

ORD 기록
ord-6983509c973240aca8c91fe06bd0f612
출처 데이터셋
uspto-grants-2016_06
특허 번호
US09376387B2

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