Benzonitrile → Benzene, 1-methyl-4-(phenylethynyl)-

HRID 2213976

반응식

HRID 2213976 반응식
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([CH3:9])=[CH:5][CH:4]=1)#[CH:2].[C:10]1(C#C)[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.C(#N)C1C=CC=CC=1>>[CH3:9][C:6]1[CH:7]=[CH:8][C:3]([C:1]#[C:2][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:4][CH:5]=1

참가 물질

4

반응물 3

HCID 7505BenzonitrileHCID 10821PhenylacetyleneHCID 13018p-Ethynyltoluene

생성물 1

HCID 3014187Benzene, 1-methyl-4-(phenylethynyl)-수율 81%

실험 절차

The procedure was identical to Example 1, with the exception that 4-ethynyltoluene (0.507 ml; 0.465 g; 4.00 mmol) was used as a substrate instead of phenylacetylene. GC analysis of the organic phase of the hydrolyzed reaction sample after 42 h at 65° C. showed the presence of 1.62 mmol (81% yield) of 1-methyl-4-(phenylethynyl)benzene, and 0.25 mmol of benzonitrile remaining in the reaction mixture.

출처 및 근거

ORD 기록
ord-6ef020ade22348b8a18215c8077c6abe
출처 데이터셋
uspto-grants-2006_09
특허 번호
US07105707B2

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