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Benzenamine, 4-(4-fluorophenoxy)- → [4-(4-Fluoro-phenoxy)-phenyl]-(2-methyl-6-nitro-phenyl)-amine

HRID 222860
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HRID 222860 반응식
F[C:2]1[C:7]([CH3:8])=[CH:6][CH:5]=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].[F:12][C:13]1[CH:26]=[CH:25][C:16]([O:17][C:18]2[CH:23]=[CH:22][C:21]([NH2:24])=[CH:20][CH:19]=2)=[CH:15][CH:14]=1.C([O-])(C)(C)C.[K+]>CS(C)=O>[F:12][C:13]1[CH:26]=[CH:25][C:16]([O:17][C:18]2[CH:23]=[CH:22][C:21]([NH:24][C:2]3[C:3]([N+:9]([O-:11])=[O:10])=[CH:4][CH:5]=[CH:6][C:7]=3[CH3:8])=[CH:20][CH:19]=2)=[CH:15][CH:14]=1
참가 물질실험 절차출처 및 근거반응 노트

참가 물질

5

반응물 3

HCID 147633Benzenamine, 4-(4-fluorophenoxy)-HCID 134709572-Fluoro-1-methyl-3-nitrobenzeneHCID 23665647Potassium tert-butoxide

생성물 1

HCID 68837567[4-(4-Fluoro-phenoxy)-phenyl]-(2-methyl-6-nitro-phenyl)-amine

시약·촉매·용매 1

HCID 679Dimethyl Sulfoxide용매

실험 절차

The product (790 mg) is obtained according to the method of stage 1 of Example 4, by using 900 μL of 2-fluoro-3-methyl-nitrobenzene and 2.6 g of 4-(4-fluoro-phenoxy)-phenylamine obtained in stage 2 of Example 5 in the presence of 2.36 g of potassium tert-butanolate in 80 mL of DMSO.

출처 및 근거

ORD 기록
ord-23473f25389845a294d96dba157a51d1
출처 데이터셋
uspto-grants-2012_06
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US08207373B2

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