Piperonal → Bis(3,4-methylenedioxy)chalcone

HRID 2236389

반응식

HRID 2236389 반응식
[CH:1]1[C:6]([CH:7]=[O:8])=[CH:5][C:4]2[O:9][CH2:10][O:11][C:3]=2[CH:2]=1.[CH3:12][C:13]([C:15]1[CH:20]=[CH:19][C:18]2[O:21][CH2:22][O:23][C:17]=2[CH:16]=1)=O.[OH-].[Na+]>C(O)C>[CH2:22]1[O:21][C:18]2[CH:19]=[CH:20][C:15]([CH:13]=[CH:12][C:7]([C:6]3[CH:1]=[CH:2][C:3]4[O:11][CH2:10][O:9][C:4]=4[CH:5]=3)=[O:8])=[CH:16][C:17]=2[O:23]1

참가 물질

5

반응물 3

HCID 8438PiperonalHCID 14798Sodium HydroxideHCID 76622Acetopiperone

생성물 1

HCID 294346Bis(3,4-methylenedioxy)chalcone

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A mixture of piperonal (460 mg) and 3,4-methylenedioxyacetophenone (500 mg) in ethanol (20 ml) was treated with 1M NaOH solution (4 ml), then the mixture was stirred overnight. The pale yellow crystalline solid was filtered off, washed with water then cold aqueous ethanol and dried to give pure bis(3,4-methylenedioxy)chalcone DC-0006B (476 mg, 53%).

후처리

  1. filtrationThe pale yellow crystalline solid was filtered off
  2. washwashed with water
  3. dry with materialcold aqueous ethanol and dried

출처 및 근거

ORD 기록
ord-ce87f20780d94c05ae7f530b9f8236b0
출처 데이터셋
uspto-grants-2010_05
특허 번호
US07714170B2

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