N-bromobutanimide → Methyl alpha-bromo-2-chlorophenylacetate
반응식
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([O:11][CH3:12])=[O:10].[Br:13]N1C(=O)CCC1=O>Br.C(Cl)(Cl)(Cl)Cl>[Br:13][CH:8]([C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[Cl:1])[C:9]([O:11][CH3:12])=[O:10]참가 물질
5
실험 절차
A stirred mixture of 36.9 g of methyl o-chlorophenylacetate, 36.0 g of N-bromosuccinimide, and 2 drops of 48% hydrobromic acid in 500 ml of carbon tetrachloride is refluxed for 20 hours and then filtered through magnesium silicate. Evaporation under reduced pressure gives methyl α-bromo-o-chlorophenylacetate as a straw-colored liquid.
후처리
- temperatureis refluxed for 20 hours
- filtrationfiltered through magnesium silicate
- customEvaporation under reduced pressure
출처 및 근거
- ORD 기록
- ord-0727808507f14d0a92aabc1d744f2376
- 출처 데이터셋
- uspto-grants-1980_11
- 특허 번호
- US04231935
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