Ethyl formate → Ethyl 2-formyl-3-(6-methyl-3-pyridyl)propionate

HRID 224872

반응식

HRID 224872 반응식
[CH3:1][C:2]1[N:7]=[CH:6][C:5]([CH2:8][CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:4][CH:3]=1.[CH:15](OCC)=[O:16].[H-].[Na+]>COCCOC>[CH:15]([CH:9]([CH2:8][C:5]1[CH:6]=[N:7][C:2]([CH3:1])=[CH:3][CH:4]=1)[C:10]([O:12][CH2:13][CH3:14])=[O:11])=[O:16]

참가 물질

5

반응물 3

HCID 8025Ethyl formateHCID 24758Sodium hydrideHCID 3018102Ethyl 3-(6-methyl-3-pyridyl)propionate

생성물 1

HCID 3018359Ethyl 2-formyl-3-(6-methyl-3-pyridyl)propionate

시약·촉매·용매 1

HCID 80711,2-Dimethoxyethane용매

실험 절차

Ethyl 3-(6-methyl-3-pyridyl)propionate was formylated with ethyl formate and sodium hydride in 1,2-dimethoxyethane to give ethyl 2-formyl-3-(6-methyl-3-pyridyl)propionate m.p. 142°-144°.

출처 및 근거

ORD 기록
ord-75b789c402b8404d813cd164565f6e5a
출처 데이터셋
uspto-grants-1980_11
특허 번호
US04234588

연결된 노트

불러오는 중…