Glycidol → 1,2-Propanediol, 3-(dodecylamino)-

HRID 2260076

반응식

HRID 2260076 반응식
[CH2:1]([NH2:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[CH2:14]1[O:16][CH:15]1[CH2:17][OH:18]>>[OH:16][CH:15]([CH2:17][OH:18])[CH2:14][NH:13][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

참가 물질

3

반응물 2

HCID 11164GlycidolHCID 13583Dodecylamine

생성물 1

HCID 1024961,2-Propanediol, 3-(dodecylamino)-

실험 절차

Dodecylamine (25.02 g, 0.13 moles) was heated at 85° C., and glycidol (10 g, 0.13 moles) was added dropwise. The reaction was heated under nitrogen for 3 hours then allowed to stir overnight. A white solid was recovered (crude yield=33.27 g), and the solid was recrystallized in hot hexane to give pure neosphingosine (yield=10.86 g).

후처리

  1. temperatureThe reaction was heated under nitrogen for 3 hours
  2. customA white solid was recovered (crude yield=33.27 g)
  3. customthe solid was recrystallized in hot hexane
  4. customto give pure neosphingosine (yield=10.86 g)

출처 및 근거

ORD 기록
ord-793658fac545448e86a238aa71eb3ed6
출처 데이터셋
uspto-grants-1995_12
특허 번호
US05476661

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