Benzoyl Peroxide → Methyl 3-(bromomethyl)benzoate

HRID 226258

반응식

HRID 226258 반응식
[CH3:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][CH:11]=1)[C:5]([O:7][CH3:8])=[O:6].[Br:12]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Br:12][CH2:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][CH:11]=1)[C:5]([O:7][CH3:8])=[O:6]

참가 물질

5

반응물 3

HCID 7187Benzoyl PeroxideHCID 7435Benzoic acid, 3-methyl-, methyl esterHCID 67184N-bromobutanimide

생성물 1

HCID 517981Methyl 3-(bromomethyl)benzoate

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매

실험 절차

A mixture of 5.5 g (36 mmol) of methyl 3-methylbenzoate, 7.1 g (39.5 mmol) of N-Bromosuccinimide and 0.44 g (1.8 mmol) of benzoyl peroxide in 75 ml of Cl4C is refluxed for 5 h. The solid is filtered and washed with Cl4C. The mother liquors are concentrated and a yellow solid is obtained which is, essentially, monobromated product. This is used in the next step without further purification.

후처리

  1. temperatureis refluxed for 5 h
  2. filtrationThe solid is filtered
  3. washwashed with Cl4C
  4. concentrationThe mother liquors are concentrated
  5. customa yellow solid is obtained which
  6. customThis is used in the next step without further purification

출처 및 근거

ORD 기록
ord-be0a5fcfdd5242d0a7929c42ccb8756c
출처 데이터셋
uspto-grants-2009_07
특허 번호
US07557212B2

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