Hydrochloric Acid → 3-Methoxy-4-phenylaminopyrrolidine hydrochloride

HRID 2293994

반응식

HRID 2293994 반응식
C(OC([N:8]1[CH2:12][CH:11]([NH:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:10]([O:20][CH3:21])[CH2:9]1)=O)(C)(C)C.[ClH:22]>CO>[ClH:22].[CH3:21][O:20][CH:10]1[CH:11]([NH:13][C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH2:12][NH:8][CH2:9]1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 214733421-t-Butoxycarbonyl-3-methoxy-4-phenylaminopyrrolidine

생성물 1

HCID 214733543-Methoxy-4-phenylaminopyrrolidine hydrochloride

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

In 100 ml of methanol was dissolved 1.98 g (0.0068 mole) of 1-t-butoxycarbonyl-3-methoxy-4-phenylaminopyrrolidine obtained as described above, and 23.5 ml of 6N hydrochloric acid was added thereto. The mixture was left to stand at room temperature overnight. The solvent was removed under reduced pressure, and the residue was washed with ethanol to obtain 1.71 g of 3-methoxy-4-phenylaminopyrrolidine hydrochloride as white powder.

후처리

  1. customobtained
  2. additionwas added
  3. waitThe mixture was left
  4. customThe solvent was removed under reduced pressure
  5. washthe residue was washed with ethanol

출처 및 근거

ORD 기록
ord-0cc71dc497264b3cb7f2d3b3eb386623
출처 데이터셋
uspto-grants-1997_11
특허 번호
US05688791

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