Tetrahydrofuran → Tert-butyl 4-(1,3-dioxoisoindolin-2-yl)-4-fluoro-4-ethoxycarbonylbutanoate

반응식

[C:27]([CH:28]=[CH2:29])(=[O:30])[O:31][C:32]([CH3:33])([CH3:34])[CH3:35].[CH:19]([N-:20][CH:21]([CH3:22])[CH3:23])([CH3:24])[CH3:25].[Li+:26].[O:1]=[C:2]1[N:3]([CH:12]([C:13](=[O:14])[O:15][CH2:16][CH3:17])[F:18])[C:4](=[O:11])[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21.[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1>>[O:1]=[C:2]1[N:3]([C:12]([C:13](=[O:14])[O:15][CH2:16][CH3:17])([F:18])[CH2:29][CH2:28][C:27](=[O:30])[O:31][C:32]([CH3:33])([CH3:34])[CH3:35])[C:4](=[O:11])[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21