Hydrochloric Acid → HCID 13648719, 화합물
반응식
[C:1]([N:5]1[C:10](=[O:11])[C:9]([Br:12])=[C:8](Br)[CH:7]=[N:6]1)([CH3:4])([CH3:3])[CH3:2].[SH-:14].[Na+].Cl>O>[C:1]([N:5]1[C:10](=[O:11])[C:9]([Br:12])=[C:8]([SH:14])[CH:7]=[N:6]1)([CH3:4])([CH3:3])[CH3:2]참가 물질
5
반응 조건
- 온도
- 60 °C
실험 절차
To 200 ml of water were added 31.0 g of 2-tert.-butyl-4,5-dibromo-3(2H)-pyridazinone and 15.8 g of 70% sodium hydrosulfide. After stirring at 60° C. for 4 hours, the resulting mixture was allowed to cool to room temperature and incorporated with about 8 ml of concentrated hydrochloric acid to lower the pH of the liquid to not higher than 2. The resulting solid was filtered off, washed with water, dried and then recrystallized from benzene/n-hexane to give 8.0 g of the intended product as white crystals of m.p. 107°-110° C. (yield: 30.4%).
후처리
- filtrationThe resulting solid was filtered off
- washwashed with water
- customdried
- customrecrystallized from benzene/n-hexane
출처 및 근거
- ORD 기록
- ord-48e0a2d377c7479c9e644d004df6c49c
- 출처 데이터셋
- uspto-grants-1989_10
- 특허 번호
- US04877787
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