Phosphorus oxychloride → HCID 13361431, 화합물

HRID 235871노트

반응식

HRID 235871 반응식
[Cl:1][C:2]1[CH:24]=[CH:23][C:5]([C:6]([NH:8][CH:9]([C:16]([C:18]2[CH:22]=[CH:21][O:20][CH:19]=2)=[O:17])[CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])=O)=[CH:4][CH:3]=1.P(Cl)(Cl)(Cl)=O>C(Cl)(Cl)Cl>[Cl:1][C:2]1[CH:24]=[CH:23][C:5]([C:6]2[O:17][C:16]([C:18]3[CH:22]=[CH:21][O:20][CH:19]=3)=[C:9]([CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])[N:8]=2)=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 24813Phosphorus oxychlorideHCID 13773131HCID 13773131, 화합물

생성물 1

HCID 13361431HCID 13361431, 화합물수율 86%

시약·촉매·용매 1

HCID 6212Chloroform용매

실험 절차

8.5 g of ethyl 3-(4-chlorobenzoylamino)-3-(3-furylcarbonyl)propionate, 50 ml of chloroform and 18.6 g of phosphorus oxychloride are treated in the same manner as described in Example 1. 6.93 g of ethyl 2-[2-(4-chlorophenyl)-5-(3-furyl)-4-oxazolyl]acetate are thereby obtained. Yield: 85.5%

출처 및 근거

ORD 기록
ord-71850a3f56d94a53831e3904cc99b3ff
출처 데이터셋
uspto-grants-1987_02
특허 번호
US04642313

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