Hydrochloric Acid → HCID 53904370, 화합물

HRID 2384068노트

반응식

HRID 2384068 반응식
C([O:3][C:4](=[O:13])[CH2:5][C:6]1[S:7][C:8]([CH2:11][CH3:12])=[N:9][N:10]=1)C.[OH-].[Na+].Cl>C(O)C>[CH2:11]([C:8]1[S:7][C:6]([CH2:5][C:4]([OH:13])=[O:3])=[N:10][N:9]=1)[CH3:12]

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 67505705(5-Ethyl-[1,3,4]thiadiazol-2-yl)-acetic acid ethyl ester

생성물 1

HCID 53904370HCID 53904370, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Next, to a solution of (5-ethyl-[1,3,4]thiadiazol-2-yl)-acetic acid ethyl ester (230 mg, 1.15 mmol) in ethanol (5 mL) is added aqueous 1M NaOH (2 mL, 2.0 mmol) and the mixture is stirred at room temperature for 18 hours. The mixture is acidified with aqueous 1M HCl and the ethanol is removed under reduced pressure. The remaining aqueous solution is lyophilized to give (5-ethyl-[1,3,4]thiadiazol-2-yl)-acetic acid.

후처리

  1. customthe ethanol is removed under reduced pressure

출처 및 근거

ORD 기록
ord-4d612c813040417f91833d76880ca0f6
출처 데이터셋
uspto-grants-2012_09
특허 번호
US08263629B2

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