Formic Acid → 2'-Methoxy-5'-nitroformanilide
반응식
[CH:1]([OH:3])=O.C(OC(=O)C)(=O)C.[CH3:11][O:12][C:13]1[CH:19]=[CH:18][C:17]([N+:20]([O-:22])=[O:21])=[CH:16][C:14]=1[NH2:15]>C1COCC1>[CH3:11][O:12][C:13]1[CH:19]=[CH:18][C:17]([N+:20]([O-:22])=[O:21])=[CH:16][C:14]=1[NH:15][CH:1]=[O:3]참가 물질
5
반응 조건
- 온도
- 55 °C
실험 절차
A mixture of formic acid (0.45 ml, 0.012 mole) and acetic anhydride (1.06 ml, 0.011 mole) was stirred at 55° C. under Ar for 2 h, and cooled to room temperature. Dry THF (10 ml) was added. To this solution was added 2-methoxy-5-nitroaniline (0.69 g, 0.004 mole). After stirring for 1 h, the suspension was evaporated in vacuo to leave the title compound as a brown solid (0.80 g, 99%).
후처리
- temperaturecooled to room temperature
- stirringAfter stirring for 1 h
- customthe suspension was evaporated in vacuo
출처 및 근거
- ORD 기록
- ord-7c7e3a1ae1ef4d34921aa31fbc44a50f
- 출처 데이터셋
- uspto-grants-1998_09
- 특허 번호
- US05801170
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