Hydrochloric Acid → 3.5-Diethyl-4-methoxybenzoic acid

HRID 2398492노트

반응식

HRID 2398492 반응식
C[O:2][C:3](=[O:16])[C:4]1[CH:9]=[C:8]([CH2:10][CH3:11])[C:7]([O:12][CH3:13])=[C:6]([CH2:14][CH3:15])[CH:5]=1.[OH-].[Na+].Cl>O>[CH2:10]([C:8]1[CH:9]=[C:4]([CH:5]=[C:6]([CH2:14][CH3:15])[C:7]=1[O:12][CH3:13])[C:3]([OH:16])=[O:2])[CH3:11]

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 53900511HCID 53900511, 화합물

생성물 1

HCID 234456633.5-Diethyl-4-methoxybenzoic acid

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A mixture of 11.6 g. (0.052 mol.) of 3,5-diethyl-4-methoxybenzoic acid methyl ester and 3.5 g. (0.09 mol.) of sodium hydroxide in 150 ml. of water is refluxed for two hours. The reaction mixture is cooled and acidified with 10% aqueous hydrochloric acid to give 3,5-diethyl-4-methoxybenzoic acid. The acid is refluxed with thionyl chloride as described in the procedure of Example 27 to give 3,5-diethyl-4-methoxybenzoyl chloride.

후처리

  1. additionA mixture of 11.6 g
  2. temperatureThe reaction mixture is cooled

출처 및 근거

ORD 기록
ord-b050c31cfced4c079c261a63c82fc88d
출처 데이터셋
uspto-grants-1977_05
특허 번호
US04024273

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