Hydrochloric Acid → HCID 178510555, 화합물

HRID 240307

반응식

HRID 240307 반응식
[O:1]=[C:2]1[C:14]2[C:9](=[N:10][C:11](C#N)=[C:12]([C:15]#[N:16])[N:13]=2)[C:8]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]1=2.Cl.[OH-:20].[Na+]>>[OH:20][C:11]1[N:10]=[C:9]2[C:8]3[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=3[C:2](=[O:1])[C:14]2=[N:13][C:12]=1[C:15]#[N:16]

참가 물질

4

반응물 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 2929299-oxo-9H-indeno(1,2-b)pyrazine-2,3-dicarbonitrile

생성물 1

HCID 178510555HCID 178510555, 화합물수율 90%

실험 절차

A suspension of 1 (5.66 g, 24.3 mmol) in aqueous NaOH (2% w/v, 81 ml) was stirred at room temperature for 16 hours. The mixture was acidified with 3N HCl to pH 1, the precipitate was collected by filtration, washed with water and dried under vacuum, affording 6 (4.88 g, 90%) as light brown solid.

후처리

  1. filtrationthe precipitate was collected by filtration
  2. washwashed with water
  3. customdried under vacuum

출처 및 근거

ORD 기록
ord-4af3784d1a4c4d8a8ef952e3236eaa83
출처 데이터셋
uspto-grants-2014_02
특허 번호
US08648076B2

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