5-Fluoroisatin → 5-fluoro-1,3-dihydro-2H-indol-2-one

HRID 24307

반응식

HRID 24307 반응식
[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[C:5]2=O>O.NN>[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[CH2:5]2

참가 물질

3

반응물 1

HCID 2365665-Fluoroisatin

생성물 1

HCID 37310125-fluoro-1,3-dihydro-2H-indol-2-one

시약·촉매·용매 1

HCID 24654Hydrazine hydrate (1:1)용매

실험 절차

5-Fluoroisatin (8.2 g) was dissolved in 50 mL of hydrazine hydrate and refluxed for 1.0 hr. The reaction mixtures were then poured in ice water. The precipitate was then filtered, washed with water and dried in a vacuum oven to afford the title compound.

후처리

  1. temperaturerefluxed for 1.0 hr
  2. customThe reaction mixtures
  3. filtrationThe precipitate was then filtered
  4. washwashed with water
  5. customdried in a vacuum oven

출처 및 근거

ORD 기록
ord-85f8d0a13c1741908216e141c66ffd9d
출처 데이터셋
uspto-grants-2005_02
특허 번호
US06855730B2

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