Benzocaine → HCID 178469015, 화합물

HRID 24743

반응식

HRID 24743 반응식
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6](=[C:13](Cl)[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:5]1=[O:21])(=O)C.[NH2:22][C:23]1[CH:33]=[CH:32][C:26]([C:27]([O:29][CH2:30][CH3:31])=[O:28])=[CH:25][CH:24]=1.[OH-].[Na+]>ClCCl.CO>[CH2:30]([O:29][C:27]([C:26]1[CH:25]=[CH:24][C:23]([NH:22]/[C:13](=[C:6]2\[C:5](=[O:21])[NH:4][C:12]3[C:7]\2=[CH:8][CH:9]=[CH:10][CH:11]=3)/[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)=[CH:33][CH:32]=1)=[O:28])[CH3:31]

참가 물질

6

반응물 3

HCID 2337BenzocaineHCID 14798Sodium HydroxideHCID 697436571-Acetyl-3-(1-chloro-1-phenyl-methylidene)-2-indolinone

생성물 1

HCID 178469015HCID 178469015, 화합물

시약·촉매·용매 2

HCID 887Methanol용매HCID 6344Dichloromethane용매

실험 절차

Prepared analogously to Example 2 from 1-acetyl-3-(1-chloro-1-phenyl-methylidene)-2-indolinone and ethyl 4-aminobenzoate in dichloromethane and subsequent treatment with sodium hydroxide solution in methanol.

출처 및 근거

ORD 기록
ord-4d11d283b74c4fe7b520a4794227a79c
출처 데이터셋
uspto-grants-2005_02
특허 번호
US06855710B2

연결된 노트

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