Sodium Hydroxide → 3-Phenoxybenzyl alcohol

HRID 247724

반응식

HRID 247724 반응식
C([O:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:7]=1)(=O)C.[OH-].[Na+]>CO>[O:12]([C:8]1[CH:7]=[C:6]([CH:11]=[CH:10][CH:9]=1)[CH2:5][OH:4])[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 170904Benzenemethanol, 3-phenoxy-, 1-acetate

생성물 1

HCID 262953-Phenoxybenzyl alcohol수율 95%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

2.42 g. (0.01 mole) of 3-phenoxybenzyl acetate, 5 cm3. of methanol and 5 cm3. of 2N sodium hydroxide solution are refluxed for three hours. Then the methanol is distilled off and the organic phase is dissolved in 30 cm3. of methylene chloride, washed with 10 cm3. of 1N hydrochloric acid solution and 10 cm3. of water. 1.90 g. of 3-phenoxybenzyl alcohol are obtained. nD20 : 1.593, yield 95%.

후처리

  1. distillationThen the methanol is distilled off
  2. dissolutionthe organic phase is dissolved in 30 cm3
  3. washof methylene chloride, washed with 10 cm3

출처 및 근거

ORD 기록
ord-1a6f3bb1de714fc18ae39f93cc964184
출처 데이터셋
uspto-grants-1987_11
특허 번호
US04709081

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