Hydrochloric Acid → 3-Phenoxybenzyl alcohol

HRID 247725

반응식

HRID 247725 반응식
C([O:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:7]=1)(=O)C.Cl>CO>[O:12]([C:8]1[CH:7]=[C:6]([CH:11]=[CH:10][CH:9]=1)[CH2:5][OH:4])[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 170904Benzenemethanol, 3-phenoxy-, 1-acetate

생성물 1

HCID 262953-Phenoxybenzyl alcohol수율 90%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

2.42 g. (0.01 mole) of 3-phenoxybenzyl acetate, 5 cm3. of methanol and 5 cm3. of 2N hydrochloric acid solution are refluxed for three hours. Then the methanol is distilled off. The organic phase is dissolved in 30 cm3. of methylene chloride, washed with 10 cm3. of water, 10 cm3. of 1N sodium hydroxide solution and 10 cm3. of water then evaporated. 1.8 g. of 3-phenoxybenzyl alcohol are obtained. nD20 : 1.593, yield 90%.

후처리

  1. distillationThen the methanol is distilled off
  2. dissolutionThe organic phase is dissolved in 30 cm3
  3. washof methylene chloride, washed with 10 cm3
  4. customof water then evaporated

출처 및 근거

ORD 기록
ord-f90801a985d04be688f6c4e70178ce4b
출처 데이터셋
uspto-grants-1987_11
특허 번호
US04709081

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