Hydrazine Sulfate → HCID 178433316, 화합물

HRID 258744

반응식

HRID 258744 반응식
[ClH:1].Cl.Cl.O[N:5]([CH2:19][CH2:20][S:21][CH2:22][C:23]1[NH:27][CH:26]=[N:25][C:24]=1[CH3:28])[C:6]([NH2:18])=[N:7][CH2:8][CH2:9][S:10][CH2:11][C:12]1[NH:16][CH:15]=[N:14][C:13]=1[CH3:17].S(O)(O)(=O)=O.[NH2:34]N.C(=O)([O-])O.[K+]>CN(C)C=O>[ClH:1].[ClH:1].[ClH:1].[NH2:34][NH:18][C:6]([NH:5][CH2:19][CH2:20][S:21][CH2:22][C:23]1[NH:27][CH:26]=[N:25][C:24]=1[CH3:28])=[N:7][CH2:8][CH2:9][S:10][CH2:11][C:12]1[NH:16][CH:15]=[N:14][C:13]=1[CH3:17]

참가 물질

5

반응물 3

HCID 24842Hydrazine SulfateHCID 516893Potassium BicarbonateHCID 178433318HCID 178433318, 화합물

생성물 1

HCID 178433316HCID 178433316, 화합물

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

A mixture of the isothiourea trihydrochloride from Example 2 (ii) (5.1 g), hydrazine sulphate (1.6 g), potassium hydrogen carbonate (7.0 g) and anhydrous dimethyl formamide (60 ml) was stirred at 70° for 3 hours. Following cooling and filtration the filtrate containing the free base was treated with an excess of ethanolic hydrogen chloride to give the title compound.

후처리

  1. temperatureFollowing cooling
  2. filtrationfiltration the filtrate
  3. additioncontaining the free base
  4. additionwas treated with an excess of ethanolic hydrogen chloride

출처 및 근거

ORD 기록
ord-bded5c2ab36842c086cd8244c474c63f
출처 데이터셋
uspto-grants-1977_07
특허 번호
US04034101

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