Isoquinoline → HCID 21425396, 화합물

HRID 258996

반응식

HRID 258996 반응식
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][N:2]=1.[C:11]1([C:17]([CH:19]([Br:26])[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[O:18])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>C1C=CC=CC=1>[Br-:26].[C:11]1([C:17]([CH:19]([C:1]2[C:10]3[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=3)[CH:4]=[CH:3][NH+:2]=2)[C:20]2[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=2)=[O:18])[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1

참가 물질

4

반응물 2

HCID 8405IsoquinolineHCID 1026302-Bromo-1,2-diphenylethan-1-one

생성물 1

HCID 21425396HCID 21425396, 화합물

시약·촉매·용매 1

HCID 241Benzene용매

실험 절차

A solution of isoquinoline(10 g) and desylbromide (10 g) in dry benzene (50 ml) was stirred at 40° for seven hours. The suspension was allowed to stand overnight, and the benzene solution decanted off. The solid was ground to a powder, washed well with ether, and dried. Yield 12.3 g (85%), m.p. 239°-241° (Found C 68.3; H 4.6; N 3.4, Required C 68.3; H 4.5; N 3.5).

후처리

  1. customthe benzene solution decanted off
  2. washwashed well with ether
  3. customdried

출처 및 근거

ORD 기록
ord-c0caa46ece104cd28f97510ceffa0466
출처 데이터셋
uspto-grants-1977_07
특허 번호
US04035499

연결된 노트

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